Gastvortrag: Prof. Dr. Dušan Mišic


Name: Vetmeduni Vienna, Hörsaal M
Beschreibung: Gebäude HA, 1. Stock (Zugang über das Hörsaalzentrum)
Straße: Veterinärplatz 1
PLZ: 1210
Stadt: Wien

Veranstaltungsbeginn: 22.08.2018 - 13:00 Uhr

Veranstaltungsende: 22.08.2018

Invitation to the guest lecture by Prof. Dr. Dušan Mišic, Department for microbiology, Faculty of Veterinary Medicine, University of Belgrade, Serbia

Title: Antibacterial activity of some non-antibiotic bioactive compounds and plant extracts suitable for usage in human and veterinary medicine”


Although studies of the antibacterial properties of plant extracts and bioactive compounds have been present in science for decades, it can be said that this area of science has been relatively neglected for years. It was shadowed by all the antibiotics and other modern medicines that pharmaceutical industry has produced. It is well known that published results prove the excellent antimicrobial activity of many plant species and extracts, but despite of these, herbal extracts and other herbal products have not found a wide application in the official medicine so far. In other words, the pharmaceutical industry and official medicine do not accept herbal supplements as medications, hence these compounds are always categorized as alternative therapies, traditional medicine, etc. However, due to the catastrophic consequences of antibiotic resistance over the past ten years, studies of the antimicrobial activity of plant extracts intensified and became a hit in science, this area suddenly become more important in the scientific literature and this issue is currently most attractive. This can be explained in one simple way: humanity and science ”used up” all the existing ideas, resources and opportunities for finding new antibiotics, thus plants remain the sole and inexhaustible source of new opportunities. Therefore, not only the demand for scientific work on plants in themed i.e. specialized journals, suddenly increased, but journals from other fields began to publish papers on antimicrobial activity of plant extracts (journals in the field of medicine, veterinary medicine, chemistry, molecular biology, pharmacology, biology, cosmetology, especially journals in the field of production and food quality). New technologies in the production of plant extracts, such as supercritical fluid extraction (SFE), due to which extracts of very complex chemical compositions and strong antimicrobial activity are obtained, have offered new application possibilities. SFE are particularly interesting because they do not contain traces of acetone, alcohol, and other organic solvent residues, inorganic salts and heavy metals, but are completely “clean” products, with no traces of impurities, which is very suitable for the modern laws, market demand and consumer requirements. SFE is perform at pressures form 40-100 MPa and temperatures around 40°C, by which degradation of thermically unstable active components is avoided. In addition, by varying temperature and pressure, it is possible to eliminate the component of the unpleasant taste or smell, and boost the amount of desired components (with strong antibacterial activity) from supercritical extracts. Also, sophisticated and expansive methods were developed for the separation of the one single desired bioactive component from a complex extract. Here, some original results and also some previously published results of antibacterial activity of supercritical extracts of lichen (Usnea barbata), hop (Humulus lupulus) and xanthohumol against some pathogenic bacteria are presented. Also some results of the in vivo application of the mentioned extracts in animals and humans will be presented. Investigations were conducted against bacterial species important for humans, animals and food industry (Staphylococcus, Streptococcus, Enterococcus, Lactobacillus, E. coli,Salmonella). Also multiresistant strains (MRSA, MRSP) were included.

Veranstaltungskategorie: Gastvortrag, Am Campus


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