Research

 Research

  •  Animal genetics focuses on nuclear and mitochondrial genomes and on the detection of hereditary defects or traits, parentage analysis, individual genotyping, and phylogenetic DNA analysis. Functional genomics encompasses RNA expression profiling and protein analyses.
  • Research in cattle reproduction aims at the understanding of mechanisms and factors influencing the developmental capacity of gametes and pre-implantation embryos in order to contribute to the tackling of the steadily increasing fertility problems in dairy cattle and to provide innovative reproduction techniques. The unit of Biology of Reproduction has a long standing expertise in transgenesis of farm animals by somatic cell nuclear transfer (SCNT) which aims at the production of pharmaceutical proteins.
  • Reverse genetics in mice has a strong focus on the molecular dissection of the JAK (Janus tyrosine kinase) – STAT (signal transducer and activator od transcription) signaling pathway in immunity to infection, (auto-)inflammation and carcinogenesis. The high evolutionary conservation of the JAK-STAT functions enables to translate the basic research findings in the mouse models to human and veterinary patients. See also the homepage of the "SFB JAK-STAT 1".