FWF Project P 25123

Mechanism of uncoupling protein activation by reactive aldehydes

Project leader: Univ.-Prof. Dr.med. Elena E. POHL

1. November 2012 - 30. April 2017

Abstract english 1

Abstract deutsch 2

 

Publications

Pohl, E.E., Jovanovic, O. (2019) The Role of Phosphatidylethanolamine Adducts in Modification of the Activity of Membrane Proteins under Oxidative Stress. Molecules 24(24):4545
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Jovanovic, O., Skulj, S., Pohl, E.E., Vazdar, M. (2019) Covalent modification of phosphatidylethanolamine by 4-hydroxy-2-nonenal increases sodium permeability across phospholipid bilayer membranes. Free Radical Biology and Medicine (143)
Abstract 4
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Zimmermann, L., Moldzio, R., Vazdar K., Krewenka, C., Pohl, E.E. (2017) Nutrient deprivation in neuroblastoma cells alters 4-hydroxynonenal-induced stress response. Oncotarget 8(5):8173-8188 (IF* 5.4).
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Annibal, A., Riemer, T., Jovanovic, O., Westphal, D., Griesser, E., Pohl, E.E., Schiller, J., Hoffmann, R., Fedorova, M. (2016) Structural, biological and biophysical properties of glycated and glycoxidized phosphatidylethanolamines. Free Radical Biology and Medicine 95:293-307 (IF* 5.98)
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Jovanovic, O., Pashkovskaya, A.A., Annibal, A., Vazdar, M., Burchardt, N., Sansone, A., Gille, L., Fedorova, M., Ferreri, C., Pohl, E.E. (2015) The molecular mechanism behind reactive aldehyde action on transmembrane translocations of proton and potassium ions. Free Radical Biology and Medicine, 89, 1067–1076 (IF* 5.98) doi: 10.1016/j.freeradbiomed.2015.10.422
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Klotzsch E., Smorodchenko A., Löfler L., Moldzio R., Parkinson E., Schütz G.J., Pohl, E.E. (2015). Superresolution microscopy reveals spatial separation of UCP4 and F0F1-ATP synthase in neuronal mitochondria. Proc. Natl. Acad. Sci. U.S.A., 112 (1): 130-135. (IF* 9.8). doi:10.1073/pnas.1415261112
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Rupprecht, A., Sittner, D., Smorodchenko, A., Hilse, K.E., Goyn, J., Moldzio R., Seiler, A. E. M., Bräuer, A.U., Pohl, E.E. (2014) Uncoupling protein 2 and 4 expression pattern during stem cell differentiation provides new insight into their putative function. PLOS ONE 9 (2): e88474
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Malingriaux, E.A., Rupprecht, A., Gille, L., Jovanovic, O., Jezek P., Jaburek, M., Pohl, E.E. (2013) Fatty acids are key in 4-hydroxy-2-nonenal-mediated activation of uncoupling proteins 1 and 2. PLOS ONE 8(10): e77786 (IF*4.2)
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Public Relations

Abstract deutsch 2