FWF Project P 25357

Mechanism of nucleotide-mediated inhibition of mitochondrial uncoupling proteins

Project leader: Univ.-Prof. Dr.med. Elena E. POHL

1. Februar 2013 - 31. Jänner 2017

Abstract english 1

Abstract deutsch 2



Kreiter, J., Rupprecht, A., Zimmermann, L., Moschinger, M., Rokitskaya, T., Antonenko, Y., Gille, L., Fedorova, M., Pohl, E. (2019) Molecular Mechanisms Responsible for Pharmacological Effects of Genipin on Mitochondrial Proteins. Biophysical Journal
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Pohl, E., Rupprecht, A., Macher, G., Hilse, K. (2019) Important Trends in UCP3 Investigation. Frontiers in Physiology
Link 4

Rupprecht, A., Moldzio, R., Mödl, B., Pohl, E. (2019) Glutamine regulates mitochondrial uncoupling protein 2 to promote glutaminolysis in neuroblastoma cells. Biochimica et Biophysica Acta (BBA) - Bioenergetics 1860 (5)
Link 5

Pashkovskaya, A., Vazdar, M., Zimmermann, L., Jovanovic, O., Pohl, P., Pohl, E. (2018) Mechanism of Long-Chain Free Fatty Acid Protonation at the Membrane-Water Interface. Biophysical Journal 114 (9)
Link 6

Hilse, K.E., Rupprecht, A., Egerbacher, M., Bardakji, S., Zimmermann, L., Seiler Wulczyn, A.E.M., Pohl, E. (2018) The Expression of Uncoupling Protein 3 Coincides With the Fatty Acid Oxidation Type of Metabolism in Adult Murine Heart. Front. Physiol. 9
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Macher, G., Koehler, M., Rupprecht, A., Kreiter, J., Hinterdorfer, P., Pohl, EE. (2018) Inhibition of mitochondrial UCP1 and UCP3 by purine nucleotides and phosphate. Biochim Biophys Acta - Biomembranes 1860. 664–672
Abstract 8

Koehler, M., Macher, G., Rupprecht, A., Zhu R., Gruber H. J., Pohl, E.E., Hinterdorfer, P. (2017) Combined Recognition Imaging and Force Spectroscopy: A new mode for mapping and studying interaction sites at low lateral density. Sci Adv Mater 9, 128–134 (IF 2.6)
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Hilse, K.E., Kalinovich, A., Rupprecht, A., Smorodchenko A., Zeitz, U., Staniek, K., Erben, R.G., Pohl, E.E. (2016) The expression of UCP3 directly correlates to UCP1 abundance in brown adipose tissue, BBA – Bioenergetics 1857, 1, 72–78 (IF* 4.78) doi: 10.1016/j.bbabio.2015.10.011
Abstract 12
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Zhu, R., Rupprecht, A., Ebner, A., Haselgruebler, T., Gruber, H.J., Hinterdorfer, P., Pohl, E.E. (2013) Mapping the nucleotide binding site of UCP1 using atomic force microscopy. JACS 135, 3640-3646 (IF 13)
Abstract 14
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Public Relations

Abstract deutsch 2