Better models can avoid animal experiments

They help scientists to reduce animal experiments: cell cultures to test the effects of substances. The more developed the cell culture systems are, the better they simulate the conditions in a living organism.

A team of scientists around Thomas Schmiedinger from the University Clinic of Radiotherapy and Radiooncology at the Medical University of Innsbruck are currently working on a system that is a better model for the living organism than existing systems. The problem of cell cultures is that the concentration of sugar, vitamins etc. is steadily decreasing and the metabolic products are increasing - despite constant supply of nutrients. In the living body, the vascular system is responsible for this exchange. Therefore the scientists try to simulate the flow conditions in the body by using the expertise of water engineers.

Article in Der STANDARD (Doris Griesser) 1