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Ass-Prof. Franziska Dengler



Most important publications:

Dengler F, Sternberg F, Grages M, Kästner S, Verhaar N (2022): Adaptive mechanisms in no flow versus low flow ischemia in equine jejunum epithelium: different paths to the same destination. Frontiers in Veterinary Science; DOI: 10.3389/fvets.2022.947482.

Dengler F, Sova S, Salo AM, Mäki JM, Koivunen P, Myllyharju J (2021): Expression and Roles of Individual HIF Prolyl 4‐Hydroxylase Isoenzymes in the Regulation of the Hypoxia Response Pathway along the Murine Gastrointestinal Epithelium. International Journal of Molecular Sciences 22(8), 4038; DOI: 10.3390/ijms22084038.
Dengler F, Kraetzig A, Gäbel G (2021): Butyrate protects porcine colon epithelium from Hypoxia-induced damage on a functional level. Nutrients 13(2), 305; DOI: 10.3390/nu13020305.

Laitakari A, Tapio J, Mäkelä KA, Herzig K, Dengler F, Gylling H, Walkinshaw G, Myllyharju J, Dimova EY, Serpi R, Koivunen P (2020): HIF-P4H-2 inhibition enhances intestinal fructose metabolism and induces thermogenesis protecting against NAFLD. Journal of Molecular Medicine. DOI: 10.1007/s00109-020-01903-0.
Delling C, Daugschies A, Bangoura B, Dengler F (2019) Cryptosporidium parvum alters glucose transport mechanisms in infected enterocytes. Parasitology Research 118 (12): 3429-41. doi: 10.1007/s00436-019-06471-y.
Dengler F, Gäbel G (2019): The fast lane of hypoxic adaptation: Glucose transport Is modulated via a HIF-hydroxylase-AMPK-axis in jejunum epithelium. International Journal of Molecular Sciences 20 (20). doi: 10.3390/ijms20204993.
Dengler F, Rackwitz R, Pfannkuche H, Gäbel G. (2018): Coping with hypoxia: adaptation of glucose transport mechanisms across equine jejunum epithelium. Journal of Equine Veterinary Science, 69: 1-10. DOI: 10.1016/j.jevs.2018.05.221.
Dengler F, Rackwitz R, Pfannkuche H, Gäbel G. (2017): Glucose transport across lagomorph jejunum epithelium is modulated by AMP-activated protein kinase (AMPK) under hypoxia. Journal of Applied Physiology (1985). DOI: 10.1152/japplphysiol.00436.2017.
Dengler F, Rackwitz R, Benesch F, Pfannkuche H, Gäbel G (2015): Both butyrate incubation and hypoxia upregulate genes involved in the ruminal transport of SCFA and their metabolites.  Journal of animal physiology and animal nutrition 99 (2), S. 379–390. DOI: 10.1111/jpn.12201.
Dengler F, Rackwitz R, Benesch F, Pfannkuche H, Gäbel G (2014): Bicarbonate-dependent transport of acetate and butyrate across the basolateral membrane of sheep rumen epithelium. Acta physiologica (Oxford, England) 210 (2), S. 403–414. DOI: 10.1111/apha.12155.