Important publications
* shared first authorship
$ shared last authorship
- Trifinopoulos J., List J., Klampfl T., Klein K., Prchal-Murphy M., Witalisz-Siepracka A., Bellutti F., Fava L.L., Heller G., Stummer S., Testori, P., den Boer M.L., Boer J.M., Marinovic S., Hoermann, G., Walter, W., Villunger, A., Sicinski, P., Sexl, V., Gotthardt, D. (2025). Cyclin C promotes B-ALL development and progression by counteracting p53-mediated stress responses. Haematologica, 110(4), 877-892. doi.org/10.3324/haematol.2024.285701
- Buri M.C., Shoeb M.R., Bykov A., Repiscak P., Baik H., Dupanovic A., David F.O., Kovacic B., Hall-Glenn F., Dopa S., Urbanus J., Sippl L., Stofner S., Emminger D., Cosgrove J., Schinnerl D., Poetsch A.R., Lehner M., Koenig X., Perie L., Schumacher T.N., Gotthardt D., Halbritter, F., Putz, E.M. (2025). Natural killer cell-mediated cytotoxicity shapes the clonal evolution of B cell leukaemia. Cancer Immunology Research, 13(3), 430-446. https://doi.org/10.1158/2326-6066.CIR-24-0189
- List J., Gattringer J., Huszarek S., Marinovic S., Neubauer H.A., Kudweis P., Putz E.M., Hellinger R., Gotthardt, D. (2024). Boosting the anti-tumor activity of natural killer cells by caripe 8 – a Carapichea ipecacuanha isolated cyclotide. Biomedicine & Pharmacotherapy 177(8), 117057. doi.org/10.1016/j.biopha.2024.117057
- Klein K.*, Kollmann S*., Hiesinger A., List J., Kendler, J., Klampfl T., Rhandawa M., Trifinopoulos J., Maurer B., Grausenburger R., Bertram A. C., Moriggl R., Rülicke T., Mullighan C., Witalisz-Siepracka A., Walter W., Hoermann G., Sexl V. $, Gotthardt D$. (2024). A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia. Blood. 143 (24), 2474-2489. https://doi.org/10.1182/blood.2023022655
- Schnoegl D., Hiesinger A., Huntington, N.D., Gotthardt D. (2023). AP-1 transcription factors in cytotoxic lymphocyte development and anti-tumour immunity. Current Opinion in Immunology. 85 (12), 102397. doi.org/10.1016/j.coi.2023.102397
- Immunological Genome Project (2020). The Immunological Genome Project: networks of gene expression in immune cells. Nature Immunology. 21(7), 700-703. doi.org/10.1038/s41590-020-0687-4
- Prinz D., Klein K., List J., Knab V., Menzl I., Leidenfrost N., Polic B., Putz E.M., Witalisz-Siepracka A., Sexl V., Gotthardt D. (2020). Loss of NKG2D in NK cells leads to increased perforin production upon long-term stimulation with IL-2. European Journal of Immunology. 50(9), 1478-1482. doi.org/10.1002/eji.201948222
- Witalisz-Siepracka A*., Gotthardt D*., Prchal-Murphy M., Didara Z., Menzl I., Prinz D., Edlinger L., Putz E.M., Sexl V. (2018). NK cell-specific CDK8 deletion enhances antitumor responses. Cancer Immunology Research. 6(4), 458-466. doi.org/10.1158/2326-6066.CIR-17-0183
- Gotthardt D., Putz E.M., Grundschober E., Prchal-Murphy M., Straka E., Kudweis P., Heller G., Bago-Horvath Z., Witalisz-Siepracka A., Cumaraswamy A.A., Gunning P.T., Strobl B., Müller M., Moriggl R., Stockmann C., Sexl V. (2016). STAT5 is a key regulator in NK cells and acts as molecular switch from tumor surveillance to tumor promotion. Cancer Discovery. 6(4), 414-429. doi.org/10.1158/2159-8290.CD-15-0732
- Gotthardt D., Putz E.M., Straka E., Kudweis P., Biaggio M., Poli V., Strobl B., Müller M., Sexl V. (2014). Loss of STAT3 in murine NK cells enhances NK cell-dependent tumor surveillance. Blood. 124(15), 2370-2381. https://doi.org/10.1182/blood-2014-03-564450
More:
https://scholar.google.com/citations?hl=de&user=jwrjPSgAAAAJ
https://www.researchgate.net/profile/Dagmar-Gotthardt
https://orcid.org/0000-0002-8416-1236