Group Roth (Computational Medicine) was established in 2022 to integrate advanced computational methods with veterinary science and agricultural research. Working on the edge between computer science and animal science, we develop theoretical machine learning algorithms alongside practical, data-driven solutions for challenges in agriculture and veterinary medicine. To this end, we evaluate and develop modern sensor technologies and data analysis methods, with applicability and cost-efficiency as recurring themes: we aim to ensure that tools can be used by non-experts at reasonable cost, even though complex technology runs in the backend, which requires interdisciplinary collaboration between developers and end-users. In this way, Group Roth developed applications ranging from assisted telemedicine and teletriage to the automatic analysis of images, video, and sensor data – including drone-based phenotyping for plant breeding, computer-vision measurement of livestock, smartphone-based diagnostics for pet owners, and route planning to locate the nearest available veterinary care – all with the same goal: optimizing resources, improving animal welfare and agricultural sustainability, and providing a basis for further innovation. Starting from scratch, the team grew to more than ten members by the end of 2023. Although it became clear in early 2025 that the group would not continue and no new projects could be started, the members of Group Roth will remain key players in computational veterinary medicine and will continue their work in this field.