* shared first authorship

$ shared last authorship

Kirkiz E, Kaufmann G, Bergqvist S, Fernández-Pernas P, Eder T, Quell L, Allram M, Manhart G, Walter W, Haferlach T, Grebien F$. Harnessing the E3 ligase SPOP for targeted degradation of the NUP98::KDM5A fusion oncoprotein. Cell Reports. 2025 Dec, https://doi.org/10.1016/j.celrep.2025.116602

Troester S, Eder T, Wukowits, N, Piontek M, Fernandez-Pernas, P, Schmoellerl J, Haladik B, Manhart G, Allram, M, Maurer-Granofszky M, Scheidegger N, Nebral K, Superti-Furga G, Meisel R, Bornhauser B, Valent P, Dworzak MN, Zuber J, Boztug K, Grebien F$. Transcriptional and epigenetic rewiring by the NUP98::KDM5A fusion oncoprotein directly activates CDK12. Nature Communications 2025 May, https://doi.org/10.1038/s41467-025-59930-9

Kodali S*, Proietti L*, Valcarcel G, Lopez-Rubio AV, Pessina P, Eder T, Shi J, Jen A, Lupion-Garcia N,Starner AC, Bartels MD, Cui Y, Sands CM, Planas-Riverola A, Martinez A, Velasco-Hernandez T, Tomas-Daza L, Alber B, Manhart G, Mayer IM, Kollmann K, Fatica A, Menendez P, Shishkova E, Rau RE, Javierre BM, Coon J, Chen Q, Van Nostrand EL, Sardina JL$, Grebien F$, Di Stefano B$. RNA. sequestration in P-bodies sustains myeloid leukaemia. Nature Cell Biology 2024 Oct;26(10):1745-1758. https://doi.org/10.1038/s41556-024-01489-6

Heyes E*, Wilhelmson AS*, Wenzel A, Manhart G, Eder T, Schuster MB, Rzepa E, Pundhir S, D'Altri T, Frank AK, Gentil C, Woessmann J, Schoof EM, Meggendorfer M, Schwaller J, Haferlach T, Grebien F$, Porse BT$. TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression. Nature Communication 2023 Oct 4;14(1):6185. https://doi.org/10.1038/s41467-023-41927-X

Ebner J*, Schmoellerl J*, Piontek M, Manhart G, Troester S, Carter BZ, Neubauer H, Moriggl R, Szakacs G, Zuber J, Kocher T, Andreeff M, Sperr WR, Valent P, Grebien F$. ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia. Nature Communications 2023 Sep 19;14(1):5709. https://doi.org/10.1038/s41467-023-41229-2

Schmoellerl J, Barbosa IAM, Minnich M, Andersch F, Smeenk L, Havermans M, Eder T, Neumann T, Jude J, Fellner M, Ebert A, Steininger M, Delwel R, Grebien F$, Zuber J$. EVI1 drives leukemogenesis through aberrant ERG activation. Blood 2023 Feb 2;141(5):453-466. https://doi.org/10.1182/blood.2022016592

Eder T, Grebien F$. Comprehensive assessment of differential ChIP-seq tools guides optimal algorithm selection. Genome Biol 2022 May 24;23(1):119. https://doi.org/10.1186/s13059-022-02686-y

Terlecki-Zaniewicz S, Humer T, Eder T, Schmoellerl J, Heyes E, Manhart G, Kuchynka N, Parapatics K,, Liberante FG, Muller AC, Tomazou EM, Grebien F$. Biomolecular Condensation of NUP98 fusion proteins drives leukemogenic gene expression. Nat Struct Mol Biol 2021, Jan 21, https://doi.org/10.1038/s41594-020-00550-w

Schmoellerl J, Barbosa IAM, Eder T, Brandstoetter T, Schmidt L, Maurer B, Troester S, Pham HTT, Sagarajit M, Ebner J, Manhart G, Aslan E, Terlecki-Zaniewicz S, Van der Veen C, Hoermann G, Duployez, N, Petit A, Lapillonne H, Puissant A, Itzykson RA, Moriggl RH, Heuser M, Meisel R, Valent P, Sexl V, Zuber J, Grebien F$. CDK6 is an essential direct target of NUP98-fusion proteins in acute myeloid leukemia. Blood 2020 Jul 23;136(4):387-400. https://doi.org/10.1182/blood.2019003267

Skucha A, Ebner J, Schmollerl J, Roth M, Eder T, Cesar-Razquin A, Stukalov A, Vittori S, Muhar M, Lu B, Aichinger M, Jude J, Muller AC, Győrffy B, Vakoc CR, Valent P, Bennett KL, Zuber J$, Superti-Furga G$, Grebien F$. MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity. Nature Communications 2018 May 18;9(1):1983. https://doi.org/10.1038/s41467-018-04329-y