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University of Veterinary Medicine Vienna

* shared first authorship

$ shared last authorship

 

  • Aung MMK, Schönefeldt S, Pfalz-Kraupp S, Wais T, Suske T, Zahma S, Franz S, Müllebner A, Feurstein G, Wagner C, Eder T, Pemovska T, Agreiter C, Pichler A, Staber PB, Hofer M, Steinborn R, Strohmer SV, Simonitsch-Klupp I, Bauer M, Wilfer A, Weber T, Potdar S, Aittokallio T, Jungherz D, Müller TA, List J, Gotthardt D, Grebien F, Bekiaris V, Herling M, Moriggl R and Neubauer HA (2026) Preclinical models of hepatosplenic γδ T-cell lymphoma with an activating STAT5B mutation display sensitivity to JAK inhibitor upadacitinib. Hemasphere, 10(4): e70345. https://doi.org/10.1002/hem3.70345
  • Ianevski A, Nader K, Nguyen J, Sorger H, Timonen S, Julia E, Pölöske D, Spirk K, Wagner C, Jungherz D, Nakano M, Kadambat Nair S, Ianevski P, Kankainen M, Dias D, Cichońska A, Pemovska T, Pirker C, Berger W, Braun T, Moriggl R, Bachy E, Mustjoki S, Herling M, Neubauer HA, Haibe-Kains B and Aittokallio T (2025) Multi-omics profiling of T-cell leukemia and lymphoma enables targeted therapeutic discovery. Cancer Research, 86(2):295-309.  https://doi.org/10.1158/0008-5472.CAN-25-0881
  • Dechow A, Timonen S, Ianevski A, Jiang Q, Wahnschaffe L, Peng Y, Jungherz D, Becker K, Neubauer HA, Schönefeldt S, de Araujo E, Gunning P, Fleck R, Schrader A, Hallek M, Pflug N, Moriggl R, Aittokallio T, Mustjoki S, Braun T and Herling M (2025) Dual STAT3/STAT5 inhibition as a novel treatment strategy in T-prolymphocytic leukemia. Leukemia, 39(6): 1435-1448. https://doi.org/10.1038/s41375-025-02577-8
  • Fortelny N*, Farlik M*, Fife V, Gorki A-D, Lassnig C, Maurer B, Meissl K, Dolezal M, Boccuni L, Geetha ARSJ, Akagha MJ, Karjalainen A, Shoebridge S, Farhat A, Mann U, Jain R, Tikoo S, Zila N, Esser-Skala W, Krausgruber T, Sitnik K, Penz T, Hladik A, Suske T, Zahalka S, Senekowitsch M, Barreca D, Halbritter F, Macho-Maschler S, Weninger W, Neubauer HA, Moriggl R, Knapp S, Sexl V, Strobl B, Decker T$, Müller M$ and Christoph Bock$ (2024) JAK-STAT signaling maintains homeostasis in T cells and macrophages. Nature Immunology, 25(5): 847-859. https://doi.org/10.1038/s41590-024-01804-1
  • Suske T, Sorger H, Manhart G, Ruge F, Prutsch N, Zimmerman MW, Eder T, Abdallah DI, Maurer B, Wagner C, Schönefeldt S, Spirk K, Pichler A, Pemovska T, Schweicker C, Pölöske D, Hubanic E, Jungherz D, Müller TA, Aung MMK, Orlova A, Pham HTT, Zimmel K, Krausgruber T, Bock C, Müller M, Dahlhoff M, Boersma A, Rülicke T, Fleck R, de Araujo ED, Gunning PT, Aittokallio T, Mustjoki S, Sanda T, Hartmann S, Grebien F, Hoermann G, Haferlach T, Staber PB, Neubauer HA, Look AT, Herling M and Moriggl R (2024) Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia. Journal of Clinical Investigation, 134(8): e168536. https://doi.org/10.1172/JCI168536
  • Schönefeldt S, Wais T, Herling M, Mustjoki S, Bekiaris V, Moriggl R and Neubauer HA (2021) The diverse roles of γδ T cells in cancer: from rapid immunity to aggressive lymphoma. Cancers, 13(24): 6212. https://doi.org/10.3390/cancers13246212
  • de Araujo ED*, Erdogan F*, Neubauer HA*, Meneksedag-Erol D, Manaswiyoungkul P, Eram MS, Seo H, Qadree AK, Israelian J, Orlova A, Suske T, Pham HTT, Boersma A, Tangermann S, Kenner L, Rülicke T, Dong A, Ravichandran M, Brown PJ, Audette GF, Rauscher S, Dhe-Paganon S, Moriggl R$ and Gunning PT$ (2019) Structural and functional consequences of the STAT5BN642H driver mutation. Nature Communications, 10(1): 2517. https://doi.org/10.1038/s41467-019-10422-7
  • Neubauer HA, Tea MN, Zebol JR, Gliddon BL, Stefanidis C, Moretti PAB, Pitman MR, Costabile M, Kular J, Stringer BW, Day BW, Samuel MS, Bonder CS, Powell JA and Pitson SM (2019) Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma. Oncogene, 38(8): 1151-1165. https://doi.org/10.1038/s41388-018-0504-9
  • Neubauer HA, Pham DH, Zebol JR, Moretti PAB, Peterson AL, Leclercq TM, Chan H, Powell JA, Pitman MR, Samuel MS, Bonder CS, Creek DJ, Gliddon BL and Pitson SM (2016) An oncogenic role for sphingosine kinase 2. Oncotarget, 7(40): 64886-64899. https://doi.org/10.1111/febs.1231410.18632/oncotarget.11714

     
  • Neubauer HA and Pitson SM (2013) Roles, regulation and inhibitors of sphingosine kinase 2. FEBS Journal, 280(21): 5317-5336. https://doi.org/10.1111/febs.12314
     

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