Sample Preparation Equipment for Small Molecule Analysis
Off-line SPE 24-Port Vacuum Chamber
Solid phase extraction (SPE) is a routinely applied step in sample preparation for small molecule analysis in biological sources like serum, urine, food and other complex matrices. It enables both removal of interfering biological matrix components as well as enhancing the concentration of analytes in LC/MS samples. Due to the complex chemistry of analytes and matrices you will have to find the optimal column type and size out of a variety of SPE sorbent materials. Bringing the columns of your choice as well as necessary solvents you can process your samples using our 24-port vacuum chamber.
The CentriVap Refrigerated Concentrator, combined with the CentriVap -104°C Cold Trap, uses centrifugal force and vacuum with or without heat to rapidly evaporate and condense solvents from biological and analytical samples. Centrifugation eliminates foaming as vacuum is applied and also concentrates the solute in the bottom of the vial. This allows recovery of solutes from different sample volumes. The unique advantage of this concentrator is that it may be cooled to -4°C to prevent damage to heat labile samples. For faster evaporation, the chamber can also be warmed during processing. As companion to the Concentrator, the CentriVap Cold Trap protects the vacuum pump by trapping moisture at -104°C, vapors and corrosive fumes as they evaporate from the samples.