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The SFB project ‘Polygenic Adaptation’ consists of three research pillars built upon specific but synergistic expertise within the SFB:

GWAS of adaptive traits

  • Magnus Nordborg: Genetic architecture in the presence of selection
  • Kelly Swarts: Adaptation to dynamically changing environments in Norway Spruce (Picea abies) forests

Modelling polygenic adaptation

  • Nick Barton: Understanding polygenic adaptation, despite polygenic selection and ancestral noise
  • Joachim Hermisson: Polygenic adaptation beyond sweeps and shifts
  • Himani Sachdeva: Can the infinitesimal model reconcile observations from GWAS and E&R?

Estimating parameters using experimental evolution

  • Neda Barghi: Genetic and adaptive architecture of polygenic traits
  • Robert Kofler: Genetic and adaptive architecture of body size variation under truncating selection in Drosophila
  • Christian Schlötterer: Polygenic adaptation with reduced genetic variation